Research HUBS

Immunity and Inflammation

Membrane Communication and remodeling 

Microbiomes in Health and Disease 

Personalized Epigenomics

Pain Forum

Rare Diseases

Disorders of the Mind and Brain

Bioengineering Materials, Cells, and Tissues

Developmental Biology

Molecular Biology of Aging

Gene Therapy and Genome Editing 

Autism and other Neurodevelopmental Disorders

 



 

 

Immunity and Inflammation

 

 

Hub director: Lior Mayo

Lior’s Lab http://liormayolab.com

The Research Hub in Immunity and Inflammation aims to elucidate the mechanisms of inflammation and immune response underlying human disease and facilitate translating laboratory discoveries into new therapies.

Research areas: 

 

  • Immunology
  • Autoimmunity
  • Immuno-oncology
  • Microbiome
  • Infectious disease
  • Neuro-immunology and neurodegenerative disease
  • Host-pathogen interactions
  • Drug development
  • New antimicrobial strategies
  • Immunotherapy

 


 

 

Membrane Communication and remodeling

 

Hub director: Ronit Sagi-Eisenberg

Intra and intercellular communication mediated by protein transport and membrane remodeling are essential processes for normal physiology, whose malfunctioning is linked with pathological pathways and disease.

 


 

 

Microbiomes in Health and Disease

 

Hub director: Elhanan Borenstein

Elhanan’s Lab http://www.borensteinlab.com

The Hub includes researchers from faculties across the university and TAU-affiliated hospitals, whose research involves microbiology, the microbiome, host/pathogen interactions and the effects and responses to antimicrobial drugs and compounds.

 

Research areas: 

 

  • Microbiology
  • Bacteria
  • Fungi
  • Viruses
  • Archea
  • Infectious disease
  • Microbiome
  • Plant pathology
  • Environment and ecology 
  • Community dynamics
  • Host-pathogen interactions
  • Antimicrobial drugs
  • Drug development
  • New antimicrobial strategies
  • Evolution and drug resistance

 


 

Personalized Epigenomics

 

Hub director: Yuval Ebenstein

Lab https://www.nanobiophotonix.com

The BioMed @ TAU Research Hub in Personalized Epigenomics brings together the community of TAU researchers involved in exploring the epigenetic basis of normal development and disease. These investigators come from across the TAU faculties and affiliated hospitals and share an interest in the processes that alter gene activity without changing the DNA sequence. This rapidly growing field encompasses research into such areas as embryonic development, plant biology, neurodegenerative disease and cancer.

 


 

 

Pain Forum

 

Hub directors: Ruth Defrin and Silviu Brill

 

Pain is major cause of suffering. Our mission is to brings together people who study or who are interested in studying pain and pain-related topics including scientists, clinicians, and students.

Our goals are to increase awareness to the problem of pain, to stimulate exchange of ideas, to encourage collaborations between hub members and mutual grant submissions and to inspire state of the art basic science and clinical studies on pain mechanisms, pain measurement, pain management and rehabilitation.

 


 

Rare Diseases

 

Hub directors:  Miguel Weil and Annick Rothschild

 

About Rare Diseases

An estimated 6% of the population is afflicted with a rare disease, a number comprised of predominately children (80%). This means that in Israel alone, rare diseases may affect around half a million people and impact the lives of many more, including parents and siblings. The health of these individuals and their families is a major societal challenge for Israel, and it requires the development of personalized adapted medicines and treatment strategies. For this reason, we formed the Research Hub in Rare Diseases at Tel Aviv University in collaboration with the Sheba Medical Center’s Institute of Rare Diseases to address the challenges linked to the care of these patients and their families.

 

Goals:

With a strong network of researchers, clinicians and other partners, the Research Hub in Rare Diseases has the potential to target user communities (including industry partners) and policymakers and thus better empower patients and parents. Specific goals include:

  • Create new networks by stimulating more collaboration between clinicians, basic researchers, education specialists, public health specialists, computer scientists and other partners
  • Combine resources and expertise to conduct and manage robust studies, develop new treatments, and raise awareness to build these networks

 

Research Areas:

  • Biomedical research in rare diseases
  • Clinical work in rare diseases
  • Cell biology
  • Animal model systems
  • Biomedical devices
  • Metabolism
  • Bioinformatics
  • Public health
  • Big Data
  • Patient information policies
  • Legislation

​​


 

Disorders of the Mind and Brain

 

Hub directors: Boaz Barak and Avi Ashkenazi

Labs

https://socsci3.tau.ac.il/boazbarak/  

https://www.ashkenazilab.com

The BioMed@TAU Research Hub Disorders of the Mind and Brain is focused on understanding the pathophysiological mechanisms of disorders involved in the brain and mind and ways to better diagnose and treat such disorders. 

 


 

Bioengineering Materials, Cells, and Tissues

 

Hub directors: Ben Maoz and Lihi Adler-Abramovich

Labs

https://www.maozlab.com

https://lihi13.wixsite.com/lihi

 

The BioMed @ TAU Research Hub Bioengineering Materials, Cells and Tissues brings together the community of people at TAU working with these components. The Hub includes researchers from faculties across the university and TAU-affiliated hospitals interested in engineering and developing materials, cells, and tissues.

 


 

Developmental Biology

 

Hub directors: Ruth Ashery-Padan, Limor Landsman, and Chen Luxenberg

Labs 

http://asherypadan.medicine.mytau.org

https://www.landsman-lab.com

https://www.luxenburglab.com

 

Developmental Biology and Stem Cell Research- Molecular and cellular processes controlling tissue differentiation and organ development during embryo development and the relevance of disease.

 


 

Molecular Biology of Aging

 

Hub director: Daniel Bar

Lab https://barlabtau.wixsite.com/website 

 


 

Gene Therapy and Genome Editing

 

Hub director: Adi Barzel

Lab https://barzellab.wixsite.com/adibarzellab

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Autism and other Neurodevelopmental Disorders

 

Hub directors: Moran Rubinstein and Ditza Zachor

Lab https://moranrub.wixsite.com/rubinsteinlab/lab-members 

 

TAU is an internationally recognized center of excellence in the study of autism and other neurodevelopmental disorders, primarily affecting children.

 

Under the leadership of Dr. Moran Rubinstein and Prof. Ditza Zachor, the Biomed@TAU Research Hub on Autism and other Neurodevelopmental Disorders will bring together scientists in this area. They will coordinate international conferences, as well as facilitate networks for competitive grant funding. TAU is home to Israel’s largest concentration of scientists and clinicians investigating all aspects of brain science, including autism. Some 1,400 TAU researcher-clinicians work in 17 affiliated hospitals, which together serve more than half of the Israeli population. These close ties ensure that research conducted in the lab has every opportunity to be translated into real-world therapies and technologies. Over 25 senior TAU scientists and their teams investigate the molecular, genetic, physiological and behavioral elements of autism.

 

The strength of TAU is the remarkable multidisciplinary, internationally renowned, and collaborative team of neuroscientists, speech therapists, geneticists, and social workers performing both basic and translational research, in consultation with leading clinicians at TAU-affiliated hospitals. Projects include identifying biomarkers for the early detection of autism, machine learning to dissect the genomics of autism, and understanding the well-being and meaning in life among families affected by autism.

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